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Schematic expression map of the PWS genomic region. PWS is caused by loss of expression of paternally inherited genes located in chrmosome 15. The extension of the deletion is critical for the severity of the phenotype, and patients that lack expression of genes in the non‐imprinted region are reported to present more serious symptons. In addition, the contribuition of the PWS‐causative genes to the phenotypic traits of the disease is given
