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. 2020 Dec 2;30(4):e13229. doi: 10.1111/jsr.13229

Table 2.

Combined included study characteristics

Demographics
Total Participants (% Female) 1,056 (56.9)
Mean Age 73.5
Diagnosis and Severity
Cognitive Diagnostic Criteria Utilised

NINCDS‐ADRDA (n = 8)

Peterson MCI Criteria (n = 3)

Albert Criteria (n = 1)

DSM‐IV (n = 1)

DSM‐V (n = 1)

DSM‐V and Peterson MCI Criteria (n = 1)

Mayo Clinic Criteria (n = 1)

Assessment of Dementia Severity Tool

MMSE (n = 10)

MoCA (n = 2)

CDR (n = 2)

TDAS (n = 1)

Not reported (n = 1)a

Baseline Cognitive Scores by Tool

Mean MMSE 22.38/30 (n = 9)

Median MMSE 28/30 (n = 1)

Mean MOCA 21.93/30 (n = 2)

Mean CDR 1.38 (n = 2)

Mean TDAS 7.57 (n = 1)

Sleep Co‐Morbidity Status

Sleep Disorders Included:‐

  • Mixed Population ± Sleep Disorder (n = 5)

  • OSA (n = 2)

  • Insomnia by DSM V Criteria (n = 2)

  • Clinically determined ‘Alteration to Sleep Pattern’ (n = 1)

Sleep Disorders Excluded:‐

  • All (n = 2)

  • Self‐Reported Sleep‐Wake Disturbance (n = 1)

  • Moderate‐Severe Sleep Disturbance (n = 1)

  • Circadian Rhythm Disorders and OSA (n = 1)

  • Significantly Reduced SWS (n = 1)

Comparison
Methodology Used

Placebo Groups (n = 4)

Active Non‐Pharmacological Control Groups (n = 3)

Non‐Treatment Arms (n = 2)

Placebo Crossover Designs (n = 5)

Healthy Population Group (n = 1)

Multiple Treatment Arms (n = 1)

Outcome
Measurement Tools

Polysomnography (n = 8)

Wrist Actigraphy (n = 4)

PSQI (n = 6)

ESS (n = 2)

FOSQ (n = 1)

ISI (n = 1)

Outcome Measure (Tool Utilised)

TST (Polysomnography n = 6, Actigraphy n = 3, PSQI n = 2)

SE (Polysomnography n = 6, Actigraphy n = 3, PSQI n = 2)

WASO (Polysomnography n = 5, Actigraphy n = 3)

SL (Polysomnography n = 6, Actigraphy n = 2, PSQI n = 2)

% REM, N1, N2, N3/N4 Sleep Duration (Polysomnography n = 7)

AI (Polysomnography n = 4)

PSQI Total (PSQI n = 6)

Other e.g. PLMI, AH, Transition, TWT, Spindle Characteristics and REM Characteristics (Polysomnography n = 4)

a

Diagnosis of MCI made utilising peterson criteria.