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. 2021 Aug 13;11(8):e048528. doi: 10.1136/bmjopen-2020-048528

Table 3.

Changes in Schedule II CNS stimulant use, 2013 and 2018

Persons, number who took CNS stimulants
2013 2018 Difference       95% CI T P Change t1–t2,(%)
All adults 2 296 473 4 128 752 1 832 279 1 006 626 2 657 932 4.35 <0.01 79.8
Gender
 Male 1 315 701 1 827 177 511 476 - 28 416 1 051 368 1.86 0.063 38.9
 Female 980 772 2 301 574 1 320 802 840 273 1 801 333 5.39 <0.01 134.7
Age group (years)
 19–24 578 917 772 502 193 585 - 224 956 612 126 0.91 0.365 33.4
 25–44 1 033 683 1 914 712 881 029 394 685 1 367 372 3.55 <0.01 85.2
 45–64 581 227 1 166 798 585 571 284 399 886 745 3.81 <0.01 100.7
 65–85 102 646 274 739 172 093 35 088 309 099 2.46 0.014 167.7
Stimulant prescriptions, number dispensed
2013 2018 Difference  95% CI p Change t1–t2 (%)
All schedule II stimulants 15 412 693 30 150 428 14 737 735 12 105 049 17 370 420 10.97 <0.01 95.6
 Amphetamine products 10 859 022 23 803 206 12 944 184 10 518 473 15 369 896 10.46 <0.01 119.2
 Methylphenidate products 4 553 672 6 347 222 1 793 550 244 341 3 342 759 2.27 0.023 39.4

CNS, central nervous system.