. 2021 Aug 2;13:700764. doi: 10.3389/fnagi.2021.700764

Table 5.

Partial correlation analysis of diffusion indices and clinical scales by controlling physical-cognitive interaction in SCD.

Tract	Diffusion index	r_p: MoCA
(a) Cognition-related partial correlation ^†
ICP (R)	MD	−0.445^*
ICP (L)	MD	−0.443^*
CST-pyramids (R)	MD	−0.423^*
Tract	Diffusion index	r_p : IPAQ-SF MET	r_p : SARC-F	r_p : Actigraphy IV	r_p : Actigraphy IS
(b) Physical activity-related partial correlation ^¶
PCR (R)	FA	0.451^*	−0.466^*	−0.752^**	0.610^*
PCR (L)	FA	0.430^*		−0.867^***
SCR (L)	FA			−0.811^**

The partial correlation analysis tested the tracts in Table 4. This table only embraced the statistically significant partial correlations (p < 0.05, uncorrected). During partial correlation analysis, the cognitive-related diffusion indices were corrected with the diffusion indices of the physical activity-related tracts, and vice versa.

p < 0.05.

^**

p < 0.01.

^***

p < 0.001.

^†

Controlled variables were the MD values of PCR (R), PCR (L), and SCR (R).

^¶

Controlled variables were the FA values of ICP (R), ICP (L), and CST pyramids (R).

r_p, partial correlation coefficient; IV, intradaily variability; IS, interdaily stability; PCR, posterior corona radiata; SCR, superior corona radiata; ICP, inferior cerebellar peduncle; CST pyramids, pyramids segment of the corticospinal tract; L, left; R, right; FA, fractional anisotropy; MD, mean diffusivity.