Skip to main content
. Author manuscript; available in PMC: 2021 Aug 16.
Published in final edited form as: J Vasc Surg. 2019 May 28;69(6 Suppl):3S–125S.e40. doi: 10.1016/j.jvs.2019.02.016

Table 1.2.

One-year major limb amputation rate by Society for Vascular Surgery (SVS) Wound, Ischemia, and foot Infection (WIfI) clinical stage

Study (year): No. of limbs at risk Stage 1 Stage 2 Stage 3 Stage 4

Cull68 (2014): 151 37 (3) 63 (10) 43 (23) 8 (40)
Zhan69 (2015): 201 39 (0) 50 (0) 53 (8) 59 (64)a
Darling71 (2016): 551 5 (0) 110 (10) 222 (11) 213 (24)
Causey70 (2016): 160 21 (0) 48 (8) 42 (5) 49 (20)
Beropoulis163 (2016): 126 29 (13) 42 (19) 29 (19) 26 (38)
Ward166 (2017): 98 5 (0) 21 (14) 14 (21) 58 (34)
Darling164 (2017): 992 12 (0) 293 (4) 249 (4) 438 (21)
Robinson72 (2017): 280 48 (2.1) 67 (7.5) 64 (7.8) 83 (17)
Mathioudakis165 (2017): 217 95 (4) 33 (3) 87 (5) 64 (6)
Tokuda167 (2018): 163 16 (0) 30 (10) 56 (10.7) 61 (34.4)
N = 2982 (weighted mean) 307 (3.2) 757 (7.0) 859 (8.7) 1059 (23.3)
Median (1-year major limb amputation) 0% 9% 9.4% 29%

The number of limbs at risk in each WIfI stage is given, with percentage of amputations at 1 year in parentheses. Means in totals (in parentheses) are weighted.

a

Falsely elevated because of inadvertent inclusion of stage 5 (unsalvageable) limbs.

HHS Vulnerability Disclosure