| Recommendations | Grade | Level of evidence | Key references | |
|---|---|---|---|---|
|
| ||||
| 4.1 | Evaluate cardiovascular risk factors in all patients with suspected CLTI. | 1 (Strong) | B (Moderate) | I.C.A.I. group,30 1997 |
| 4.2 | Manage all modifiable risk factors to recommended levels in all patients with suspected CLTI. | 1 (Strong) | B (Moderate) | Armstrong,224 2014 Faglia,32 2014 |
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