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. Author manuscript; available in PMC: 2021 Aug 16.
Published in final edited form as: J Vasc Surg. 2019 May 28;69(6 Suppl):3S–125S.e40. doi: 10.1016/j.jvs.2019.02.016
Research priorities

4.1 Define the optimal antithrombotic regimen (safety and efficacy) in patients with CLTI to reduce cardiovascular and limb-specific events.
4.2 Define treatment targets and optimal dosing for lipid-lowering agents in the CLTI population.
4.3 Identify biomarkers predictive of clinical events in the CLTI population that may serve as targets for therapy.
4.4 Identify effective smoking cessation strategies for patients with advanced PAD and CLTI.
4.5 Identify the type of analgesia that is most effective in patients with chronic pain secondary to CLTI.