Recommendations	Grade	Level of evidence	Key references
10.1	Continue best medical therapy for PAD, including the long-term use of antiplatelet and statin therapies, in all patients who have undergone lower extremity revascularization.	1 (Strong)	A (High)	Abbruzzese,125 2004 Henke,126 2004 Brown,127 2008 Bedenis,128 2015 Suckow,129 2015
10.2	Promote smoking cessation in all CLTI patients who have undergone lower extremity revascularization.	1 (Strong)	A (High)	Hobbs,130 2003 Willigendael,131 2005
10.3	Consider DAPT (aspirin plus clopidogrel) in patients who have undergone infrainguinal prosthetic bypass for CLTI for a period of 6 to 24 months to maintain graft patency.	2 (Weak)	B (Moderate)	Brown,127 2008 Belch,132 2010 Gassman,133 2014 Bedenis,128 2015
10.4	Consider DAPT (aspirin plus clopidogrel) in patients who have undergone infrainguinal endovascular interventions for CLTI for a period of at least 1 month.	2 (Weak)	C (Low)	Cassar,134 2005 Bhatt,135 2006 Tepe,136 2012 Strobl,137 2013
10.5	Consider DAPT for a period of 1 to 6 months in patients undergoing repeated catheter-based interventions if they are at low risk for bleeding.	2 (Weak)	C (Low)	Cassar,134 2005 Tepe,136 2012 Strobl,137 2013
10.6	Observe patients who have undergone lower extremity vein bypass for CLTI on a regular basis for at least 2 years with a clinical surveillance program consisting of interval history, pulse examination, and measurement of resting APs and TPs. Consider DUS scanning where available.	Good practice statement
10.7	Observe patients who have undergone lower extremity prosthetic bypass for CLTI on a regular basis for at least 2 years with interval history, pulse examination, and measurement of resting APs and TPs.	Good practice statement
10.8	Observe patients who have undergone infrainguinal endovascular interventions for CLTI in a surveillance program that includes clinical visits, pulse examination, and noninvasive testing (resting APs and TPs).	Good practice statement
10.9	Consider performing additional imaging in patients with lower extremity vein grafts who have a decrease in ABI ≥0.15 and recurrence of symptoms or change in pulse status to detect vein graft stenosis.	Good practice statement
10.10	Offer intervention for DUS-detected vein graft lesions with an associated PSV of >300 cm/s and a PSV ratio >3.5 or grafts with low velocity (midgraft PSV <45 cm/s) to maintain patency.	1 (Strong)	B (Moderate)	Mills,138 2001
10.11	Maintain long-term surveillance after surgical or catheter-based revision of a vein graft, including DUS graft scanning where available, to detect recurrent graft-threatening lesions.	1 (Strong)	B (Moderate)	Landry,139 2002 Nguyen,140 2004
10.12	Consider arterial imaging after endovascular intervention for failure to improve (wound healing, rest pain) or a recurrence of symptoms to detect restenosis or progression of pre-existing disease.	2 (Weak)	C (Low)	Bui,141 2012
10.13	Consider reintervention for patients with DUS-detected restenosis lesions >70% (PSV ratio >3.5, PSV >300 cm/s) if symptoms of CLTI are unresolved or on a selective basis in asymptomatic patients after catheter-based interventions.	2 (Weak)	C (Low)	Humphries,142 2011