Global vascular guidelines on the management of chronic limb-threatening ischemia

. Author manuscript; available in PMC: 2021 Aug 16.

Published in final edited form as: J Vasc Surg. 2019 May 28;69(6 Suppl):3S–125S.e40. doi: 10.1016/j.jvs.2019.02.016

	Recommendations

11.4	To facilitate sufficient enrollment, limit RCT exclusion criteria to those that are deemed essential to trial integrity.
11.5	Design RCTs, prospective cohort studies, and registries that are specific to CLTI.
11.6	Use an integrated, limb-based threatened limb classification system (eg, WIfI) and a whole limb anatomic classification scheme (eg, GLASS) to describe the characteristics and outcomes of CLTI patients who are enrolled.