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. Author manuscript; available in PMC: 2021 Aug 16.
Published in final edited form as: J Vasc Surg. 2019 May 28;69(6 Suppl):3S–125S.e40. doi: 10.1016/j.jvs.2019.02.016
Recommendation
11.10 Include a time-integrated measure of clinical disease severity (such as freedom from CLTI) in the CLTI trial design to describe the total impact of comparator CLTI interventions.
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