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. Author manuscript; available in PMC: 2021 Aug 16.
Published in final edited form as: J Vasc Surg. 2019 May 28;69(6 Suppl):3S–125S.e40. doi: 10.1016/j.jvs.2019.02.016
Research priorities

11.1 Design well-constructed RCTs that address clinically relevant issues regarding the management of CLTI.
11.2 Clarify angiosome-based vs indirect tibial revascularization.
11.3 Identify the relative value of endovascular vs surgical therapy.
11.4 Validate specific anatomic scenarios outlined within GLASS.
11.5 Validate the WIfI system across specific grade levels.
11.6 Develop a reliable, real-time assessment tool for postintervention foot and wound perfusion.
11.7 Develop consensus definitions of postintervention patency and standardized patency-based end points relevant to CLTI interventions and trials.
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