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. 2021 Aug 2;12:699684. doi: 10.3389/fimmu.2021.699684
SLE Systemic lupus erythematosus
miRNAs microRNAs
auto-Abs autoantibodies
DCs dendritic cells
TLR Toll-like receptor
NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells
pri-miRNAs primary RNA transcripts
RNase III enzyme ribonuclease III enzyme
pre-miRNA precursor miRNAs
RISC RNA-induced silencing complex
mRNA messenger RNA
3’-UTR 3’-untranslated region
mDC myeloid DC
pDC plasmacytoid DC
Blimp1 B lymphocyte–induced maturation protein-1
SOCS suppressor of cytokine signaling
SHIP-1 SH2 domain-containing inositol 5’-phosphatase 1
JAK-STAT Janus kinase/signal transducer and activator of transcription
PI3K phosphatidylinositol 3-kinase
AKT protein kinase B
BCR B cell receptor
LYN Lck/Yes novel tyrosine kinase
FcγRIIb Fcγ receptor IIb
PTEN phosphatase and tensin homolog
Bcl-2 B cell lymphoma-2
EBF1 expression of Early B cell factor 1
Tfh cells follicular helper T cells
DNMTs DNA methyltransferases
RASGRP1 rasguanyl-nucleotide-releasingprotein1
TNFSF tumour necrosis factor superfamily
LAF-1 lymphocyte function-associated antigen 1
SLAM signaling lymphocytic activation molecule
IL-10 interleukin 10
SAP SLAM associated protein
IgG immunoglobulin G
STAT-1 activator of transcription-1
API5 apoptosis inhibitory protein 5
Foxp3 forkhead box P3
Teff cell effector T cell
Treg cells regulatory T cells
PBMCs peripheral blood mononuclear cells
TNF α tumour necrosis factor α
cAMP cyclic adenosine monophosphate
Th cell T helper cell
IFN-1 type 1 interferon
MHC I major histocompatibility complex I
CXCL chemokine (C-X-C motif) ligand
CXCR 3 CXC chemokine receptors 3
APCs antigen-presenting cells
RANTES regulated on activation, normal T cell expressed and secreted