Table 2.
Comparison of conversion rates and yields of 4-AD, ADD and 9OH-AD from phytosterol by a variety of Mycobacterium strains
| Strain | Phytosterol concentration (g/L) |
Yield | Conversion rate | References | ||
|---|---|---|---|---|---|---|
| 4-AD (g/L) | ADD (g/L) | 9OH-AD (g/L) | ||||
| 4-AD-producing strains | ||||||
| Mycobacterium sp. ATCC 25795 | 15 | 6.85 | 5.57 | N/A | 45.67% (4-AD); 37.13% (ADD) | [64] |
| Mycobacterium sp. B-3683 | 5 | 2.35 | N/A | N/A | 47% | [65] |
| Mycobacterium sp. B-3805 | 20 | 7.4 | N/A | N/A | 37% | [51] |
| Mycobacterium smegmatis MC2 155 | 10 | 8.8-9.0 | 1.0-1.1 | N/A | N/A | [26] |
| Mycobacterium sp. HGMS2 | 10 | 5.62 | 1.30 | 0.30 | 47.2% | This work |
| Mycobacterium sp. HGMS2 | 80 | 31.4 | 6.26 | 0.88 | 40.6% | This work |
| Mycobacterium sp. HGMS2Δkstd211 + ΔkshB122 | 10 | 6.22 | NO | NO | 51.6% | This work |
| Mycobacterium sp. HGMS2Δkstd211 + ΔkshB122 | 80 | 38.3 | NO | NO | 48.7% | This work |
| ADD-producing strains | ||||||
| Mycobacterium neoaurum NwIB-04 | 15 | 0.096 | 4.94 | N/A | 32.93% | [32] |
| Mycobacterium neoaurum NwIB-01 | 0.4 | N/A | 0.174 | N/A | 43.5% | [31] |
| Mycobacterium sp. HGMS2kstd2 + Δkstd211+ΔkshB122 | 10 | NO | 4.12 | NO | 44.2% | This work |
| Mycobacterium sp. HGMS2kstd2 + Δkstd211+ΔkshB122 | 80 | NO | 34.2 | NO | 42.5% | This work |
| 9OH-AD-producing strains | ||||||
| Mycobacterium sp. MS136 | 13 | N/A | N/A | 6.0 | 40% | [21] |
| Mycobacterium neoaurum 25795 mutant | 20 | N/A | N/A | 10.27 | 51.2% | [63] |
| Mycobacterium neoaurum ATCC 25795 mutant | 15 | N/A | N/A | 6.20 | 41.33% | [30] |
| Mycobacterium sp. HGMS2kshA51 + Δkstd211+ΔkshA226 | 10 | NO | NO | 4.2 | 44.2% | This work |
| Mycobacterium sp. HGMS2kshA51 + Δkstd211+ΔkshA226 | 80 | NO | NO | 37.2 | 40.3% | This work |
N/A data not available, SD significant detectable, NO not observable