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Deregulation of EPAS1 DNA number and mRNA expression in colorectal carcinoma (CRC) and cancer cells. (A) Tissues from CRC had shown a significant amplified EPAS1 DNA number when compared to that of matched non‐cancerous samples. (B) Likewise, CRC patients showed a significant EPAS1 overexpression when compared to that of matched non‐cancerous samples (p < 0.05). (C) Colon cancer cells derived from different stages exhibited higher EPAS1 mRNA when compared with non‐cancer cells (FHC)
