TABLE 1.
Patient characteristics at the time of recurrence
| VETC (+) | VETC (−) | |||||
|---|---|---|---|---|---|---|
| Variables | RHR | RFA | p | RHR | RFA | p |
| Age, y | 49.5 ± 10.9 | 48.9 ± 10.7 | 0.822 | 51.5 ± 10.3 | 49.4 ± 11.2 | 0.498 |
| Sex | 1.000 | 0.647 | ||||
| Male | 47 | 64 | 78 | 108 | ||
| Female | 3 | 5 | 10 | 11 | ||
| HBsAg | 0.427 | 0.201 | ||||
| Positive | 41 | 61 | 76 | 94 | ||
| Negative | 9 | 8 | 12 | 25 | ||
| Background liver | 0.708 | 0.137 | ||||
| Normal | 19 | 29 | 34 | 34 | ||
| Cirrhosis | 31 | 40 | 54 | 85 | ||
| Histological grade | 0.850 | 0.776 | ||||
| Well differentiated | 21 | 27 | 38 | 48 | ||
| Poorly differentiated | 29 | 42 | 50 | 71 | ||
| Microvascular invasion | 0.136 | 0.472 | ||||
| Present | 18 | 35 | 14 | 24 | ||
| Absent | 32 | 34 | 74 | 95 | ||
| ALB at recurrence, g/l | 41.9 ± 6.6 | 42.0 ± 3.3 | 0.154 | 42.6 ± 5.8 | 42.4 ± 7.7 | 0.488 |
| TBIL at recurrence, umol/l | 15.5 ± 4.7 | 14.7 ± 4.9 | 0.922 | 15.5 ± 5.6 | 15.2 ± 5.9 | 0.147 |
| HGB at recurrence, g/l | 143.6 ± 17.8 | 143.9 ± 16.8 | 0.421 | 144.3 ± 22.4 | 142.7 ± 24.0 | 0.777 |
| AFP at recurrence, ng/ml | 0.838 | 0.884 | ||||
| > 20 | 35 | 50 | 56 | 77 | ||
| ≤ 20 | 15 | 19 | 32 | 42 | ||
| Child‐Pugh score at recurrence | 0.488 | 0.363 | ||||
| 5 | 42 | 54 | 73 | 94 | ||
| 6 | 8 | 15 | 13 | 25 | ||
| Tumor size at recurrence, cm | 2.4 ± 0.6 | 2.2 ± 0.5 | 0.472 | 2.4 ± 0.5 | 2.3 ± 0.4 | 0.630 |
| Tumor multiplicity at recurrence | 0.451 | 0.158 | ||||
| Solitary | 44 | 57 | 75 | 91 | ||
| Multiple | 6 | 12 | 13 | 28 | ||
| Time to recurrence | 0.192 | 1.000 | ||||
| < 1 year | 23 | 27 | 34 | 54 | ||
| ≥ 1 year | 41 | 28 | 46 | 73 | ||
| ECOG‐PS | 0.709 | 0.792 | ||||
| 0–1 | 53 | 59 | 93 | 99 | ||
| 2 | 4 | 3 | 8 | 7 | ||
Abbreviations: AFP, α‐fetoprotein; ALB, albumin; ECOG‐PS, Eastern Cooperative Oncology Group Performance Status; HGB, hemoglobin; RFA, radiofrequency ablation; RHR, repeat hepatic resection; TBIL, total bilirubin; VETC, vessels encapsulating tumor clusters