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. 2021 Aug 16;14(10):1299–1312. doi: 10.1016/j.jiph.2021.08.014

Table 6.

Effect and management of corona in different phenotypes.

L-Phenotype H-Phenotype
Low elastance (HLC) High elastance (LLC)
Low ventilation perfusion ratio High shunt from right to left
The low weight of lung The high weight of lung
Low recruitability High recruitability
PaO2/FiO2 = 95 mmHg PaO2/FiO2 = 84 mmHg
Non-intubated patients Severe ARDS treated patients
-HFNC, CPAP, NIV -PEEP is higher,
Intubated patients: -Prone position lying
-Volumes greater than 6 mg/kg (up to 8−9 mg/kg) can be ventilated for hypercapnic patients -Extracorporeal support
-PEEP reduced 8−10 cm H2O
-Prone positioning only as a rescue maneuver