Table 2.
Laboratory findings in elderly patients with COVID-19
| Total median (IQR) |
Survivor median (IQR) |
Non-survivor median (IQR) |
P* | |
|---|---|---|---|---|
| Leukocytes (109/L) | 6.40 (4.54–9.00) | 5.96 (4.53–7.85) | 8.16 (5.58–12.50) | 0.003 |
| Lymphocytes (109/L) | 0.84 (0.54–1.18) | 0.88 (0.68–1.34) | 0.55 (0.36–0.88) | < 0.001 |
| Neutrophils (109 /L) | 4.90 (3.10–7.44) | 4.26 (2.85–6.10) | 7.03 (4.30–7.03) | < 0.001 |
| ALT (U/L) | 25 (18–40) | 26 (18–42) | 23 (18–35) | 0.24 |
| AST (U/L) | 31 (21–46) | 30 (21–41) | 42.5 (26–57) | 0.007 |
| LDH (U/L) | 309 (223–467) | 263 (214–359) | 478.5 (363–584) | < 0.001 |
| CK (U/L) | 63 (42–114) | 60 (41–93) | 78 (45–215) | 0.034 |
| Albumin (g/L) | 34.26 ± 4.05 | 34.56 ± 4.04 | 33.51 ± 4.02 | 0.999 |
| Globulin (g/L) | 25.3 (22.0–28.4) | 24.7 (21.8–28.3) | 25.7 (22.5–29.0) | 0.14 |
| Creatinine (μmol/L) | 68.0 (56.0–92.0) | 66.0 (57.0–81.0) | 81.0 (54.0–120.0) | 0.033 |
| BUN (mmol/L) | 6.50 (4.85–9.55) | 6.20 (4.70–7.90) | 9.90 (6.10–16.45) | < 0.001 |
| CD3 (/μL) | 455.5 (267–709) | 558 (377–840) | 244 (142–397) | < 0.001 |
| CD4 (/μL) | 281 (165–484) | 333 (212–559) | 165 (96–267) | < 0.001 |
| CD8 (/μL) | 145 (67–255) | 191 (96–267) | 64 (42–139) | < 0.001 |
| CD19 (/μL) | 109 (60–163) | 114 (68–183) | 75 (42–138) | 0.016 |
| CD16 + CD56 (/μL) | 101 (59–210) | 116 (72–247) | 69 (39–118) | 0.002 |
| CRP (mg/L) | 53.85 (15.25–94.10) | 37.65 (11.40–70.80) | 107.3 (55.2–188.0) | < 0.001 |
| D-dimer (mg/L) | 1.61 (0.68–5.96) | 1.09 (0.50–3.26) | 6.32 (2.37–17.44) | < 0.001 |
| CD4/CD8 | 2.10 (1.39–3.14) | 2.03 (1.39–3.16) | 2.22 (1.30–3.03) | 0.685 |
| Procalcitonin (ng/mL) | 0.093 (0.052–0.189) | 0.076 (0.046–0.137) | 0.166 (0.085–0.552) | < 0.001 |
| C3 (g/L) | 0.970 ± 0.200 | 0.989 ± 0.196 | 0.931 ± 0.201 | 0.835 |
| C4 (g/L) | 0.244 (0.186–0.310) | 0.241 (0.187–0.301) | 0.254 (0.152–0.328) | 0.955 |
| IgM (g/L) | 0.822 (0.597–1.140) | 0.779 (0.562–1.090) | 1.030 (0.715–1.320) | 0.059 |
| IgG (g/L) | 12.4 (10.4–15.0) | 12.1 (9.5–15.0) | 12.9 (11.2–14.9) | 0.219 |
| IgA (g/L) | 2.70 (2.12–3.44) | 2.59 (1.98–3.32) | 3.19 (2.42–3.63) | 0.036 |
| IgE (IU/mL) | 37.6 (18.3–98.7) | 32.8 (18.3–92.4 | 70.3 (27.8–164.0) | 0.046 |
*P values were calculated by the Student’s t-test or Wilcoxon test for continuous variables. ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; CRP, C-reactive protein; LDH, lactate dehydrogenase; BUN, blood urea nitrogen; C3, Complement component 3; C4, Complement component 4; IgM, immunoglobulin M; IgG, immunoglobulin G; IgA, immunoglobulin A; IgE, immunoglobulin E; CD, cluster of differentiation. *P < 0.05