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a Copper absorption by various organs such as muscles, liver and skeletal system and its expulsion via sweat and urine. Reprinted from (Bost et al. 2016), with permission from Elsevier. b Copper metabolism inside human body upon absorption by stomach and small intestine and the mechanism by which copper compounds being transferred to different parts of human body. Reprinted from (Wang et al. 2021), with permission from Elsevier
