Table 1.
Laboratory and investigation results.
| Test (normal range with units) | Result |
|---|---|
| Hemoglobin (13.2–17.7 g/dL) | 13.9 |
| Platelets (150–400 K/mm3) | 165 |
| White blood count (3.7–10.5 K/mm3) | 7.7 |
| Blood urea nitrogen (10–20 mg/dL) | 13 |
| Creatinine (0.6–1.2 mg/dL) | 0.9 |
| Liver function test | Normal |
| Cerebrospinal fluid (CSF) analysis-lumbar puncture done at 5 months after SARS-CoV-2 positive test | |
| Color | Clear |
| Total protein (15–45 mg/dL) | 20 |
| Glucose (40–75 mg/dL) | 57 |
| White cell count (0–5/mm3) | 2 |
| Microbiological studiesa | Negative |
| CSF meningitis and encephalitis panelb | Negative |
| Multiple sclerosis screen | Negative, no oligoclonal bands in serum or CSF |
| CSF IgG index (0.28–0.66 normal ratio) | 0.47 |
| Paraneoplastic autoantibodies in serum and CSFc | Negative |
| Erythrocyte sedimentation rate (0–15 mm/h) | 15 |
| Hemoglobin A1c (4.8%–6.0%) | 5.6% |
| Serum blood glucose (65–139 mg/dL) | 98 |
| Thyroid function tests | Normal |
| Serum vitamin B12 (232–1,245 pg/mL) | 1,068 |
| Serum protein electrophoresis | Normal |
| Nerve conduction study (NCS) and electromyography(EMG) done for numbness and tingling | Motor and sensory conduction studies normal. Left tibial nerve F-wave latency was normal when corrected for temperature. Normal EMG |
| Computed tomography of the head without contrast | Normal |
| Computed tomography of the larynx/soft tissue neck with contrast | Normal |
| Computed tomography of the lung without contrast (inspiratory and expiratory scan done at 3 months after SARS-CoV-2-positive test) | Minimal lateral peripheral air trapping of the left lateral lower lobe. No evidence of any infectious process |
| Pulmonary function test | Spirometry normal, normal flow volume loops |
| Two-dimensional transthoracic echocardiogram | Ejection fraction 55%–60%, normal ventricular size, normal right ventricular function |
CSF: cerebrospinal fluid; NCS: nerve conduction study; EMG: electromyography.
Gram stain, bacterial culture-aerobic and anerobic, fungal cultures, CSF cryptococcal Antigen.
PCR assays for detection of Enterovirus, E. coli, Haemophilis influenzae, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pnemoniae, cytomegalovirus, Perechovirus, Herpes Simplex Virus 1 and 2, Human Herpesvirus 6, varicella zoster virus, Cryptococcus neoformans/gattii.
Encephalitis profile: anti-NMDA, anti-neuronal nuclear antibody (ANNA), Type 1/ 2/ 3, Purkinje cell cytoplasmic antibody type 1/2/Type Tr, amphiphysin antibody, Type 1, GAD65, AMPA-R antibody CBA, GABA-B-R antibody CBA, leucine-rich glioma inactivated protein 1 IgG, CASPR2 IgG, AChR ganglionic neuronal antibody, N-type calcium channel antibody, P/Q-type calcium channel antibody.