Table 6.
Multivariable analysis of factors associated with 90-day mortality
| Variable | Univariate | Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P | Adjusted HR (95% CI) | P | |
| Age group | ||||
| 65-74 | Reference | -- | Reference | -- |
| 75-84 | 5.47 (0.49-60.59) | 0.166 | 0.43 (0.004-47.99) | 0.729 |
| 85+ | 29.44 (2.62-330.25) | 0.006 | 20.39 (0.86-484.28) | 0.062 |
| BMI (kg/m2) - continuous | 1.11 (1.02-1.21) | 0.019 | 1.16 (1.005-1.33) | 0.042 |
| ECOG performance status | ||||
| 0 | Reference | -- | Reference | -- |
| 1-2 | 5.79 (0.52-64.13) | 0.152 | 4.66 (0.16-133.25) | 0.369 |
| 3-4 | 259.67 (20.66-3263.89) | <0.001 | 7686.5 (10.98-5379219.9) | 0.007 |
| 5 or more comorbidities | ||||
| No | Reference | -- | Reference | -- |
| Yes | 6.53 (1.08-39.36) | 0.041 | 1.926 (0.08-44.86) | 0.683 |
| Procedure | ||||
| Major | Reference | -- | ||
| Minor | 0.58 (0.06-5.25) | 0.629 | ||
| Major complication (grade 3-5) | ||||
| No | Reference | -- | Reference | -- |
| Yes | 55.02 (8.84-342.34) | <0.001 | 170.01 (5.94-4866.26) | 0.003 |
| Frail | ||||
| No | Reference | -- | Reference | -- |
| Yes | 8.47 (1.39-51.44) | 0.020 | 0.03 (0-3.83) | 0.152 |
BMI, body mass index; ECOG, Eastern Cooperative Oncology Group
All variables were tested for multicollinearity. Clinically significant variables and variables with p<0.2 on univariate analysis were included in the multivariable analysis.