Table 1.
Characteristics of the enrolled patients.
| Case NO. | Age | Operation date |
Pathological diagnosis | Chemotherapy regimens after operation | *serum CA125 before 6B11-OCIK treatment (U/ml) | CT image of patients before 6B11-OCIK treatment | 6B11-OCIK treatment(D1, D6, D11, D25, D39) |
|---|---|---|---|---|---|---|---|
| 1 | 44 | 1/5/2016 | High-grade serous carcinoma stage IIIC | 2/2016-6/2017: 3-step chemotherapy: liposome paclitaxel + loplatin *7; Cyclophosphamide + etoposide *6; Cyclophosphamide + carboplatin *2. 6/2017: Recurred with drug-resistant 8/2017-10/2017: Carboplatin + paclitaxel *4 11/2017-3/2018: gemcitabine + bevacizumab (28 days therapy in weeks 1、8、15) 5/2018: albumin paclitaxel + bevacizumab weekly therapy *3 |
Before initial operation: 815 8/15/2016:322 8/21/2017:117 10/30/2017:566 3/8/2018:122 |
Low-density nodules at the posterior margin of segment S6 of the liver and multiple intrahepatic nodules were considered as metastatic tumors. Multiple nodular peritoneum thickening suggested implantation metastasis. Lymph nodes were found in abdominal pelvic cavity and bilateral iliac, among which multiple enlarged were found near the right iliac vessels, and lymphatic metastasis was considered. | 8/16/2018 8/22/2018 8/29/2018 9/17/2018 9/30/2018 |
| 2 | 55 | 2/23/2018 | High-grade serous carcinoma stage IIIC | 2/2018-7/2018: paclitaxel liposome (240mg) + carboplatin(500mg) *5; paclitaxel (210mg) + carboplatin (500mg). | Before initial operation:5000+ 9/25/2018:34.52 10/24/2018:91.61 11/17/2018:161.2 |
Multiple small lymph nodes were found in pelvic cavity and retroperitoneum; Splenic tubercle*; Left adrenal gland with poor shape* | 11/28/2018 12/3/2018 12/7/2018 12/28/2018 1/9/2019 |
| 3 | 52 | 9/24/2014 11/29/2016 4/24/2018 |
Stage IIIB of high-grade serous adenocarcinoma | 10/2014-5/2015: Paclitaxel + carboplatin *8; 12/2016-5/2017:TC*3, taxol (240mg) +eloxatin (200mg) *1, IAP*2; 5/2018-12/2018:paclitaxel Liposome(150-210mg)*10+ Arsenious acid and sodium chloride injection (10mg) (7-10 daily a month*8 months); 12/2018: fluorouracil(1.45g) *3; Doxorubicin *1(60mg) |
Before initial operation:338.2 3/2/2018:127.6 3/29/2018:239.4 5/14/2018:308.5 |
Multiple enlarged lymph nodes were found near the abdominal aorta and left iliac vessels. Metastatic tumors were considered | 6/17/2019 6/21/2019 6/26/2019 7/8/2019 7/18/2019 |
*Normal serum CA125 level was ≤35 U/ml.