Table 1.
Characteristics of the study population
| All (N=39) | Original cohort (N=19) | Expansion cohort (N=20) | |
|---|---|---|---|
|
| |||
| Age (years) – median (range) | 54 (27, 77) | 53 (32, 70) | 59 (27, 77) |
| Sex | |||
| Female | 7 (18) | 2 (11) | 5 (25) |
| Male | 32 (82) | 17 (89) | 15 (75) |
| Karnofsky performance status | |||
| 70% | 2 (5) | 0 | 2 (10) |
| 80% | 13 (33) | 8 (42) | 5 (25) |
| 90% | 24 (62) | 11 (58) | 13 (65) |
| Histology subtype | |||
| Unclassified RCC, papillary features | 24 (61) | 14 (74) | 10 (50) |
| Papillary RCC | 14 (36) | 5 (26) | 9 (45) |
| Translocation-associated RCC, papillary features | 1 (3) | 0 | 1 (5) |
| Nephrectomy | |||
| Yes | 29 (74) | 13 (68) | 16 (80) |
| No | 10 (10) | 6 (32) | 4 (20) |
| IMDC risk group | |||
| Favorable | 9 (23) | 6 (32) | 3 (15) |
| Intermediate | 24 (62) | 11 (58) | 13 (65) |
| Poor | 6 (15) | 2 (10) | 4 (20) |
Abbreviations: IMDC, International Metastatic Renal Cell Carcinoma Database Consortium