. Author manuscript; available in PMC: 2021 Aug 16.

Published in final edited form as: J Bone Miner Res. 2014 Nov;29(11):2405–2413. doi: 10.1002/jbmr.2265

Table 2.

Cancellous Structural Characteristics at the Distal Femoral Metaphysis Measured Via μCT

	SHAM (a)	ORX (b)	ORX+AN (c)	ORX+TE (d)	ORX+TE+AN (e)	ORX+TREN (f)	ORX+TREN+AN (g)
BV/TV, %	17.6 ± 0.6^b^,c	13.3 ± 0.3^a^,d^,e^,f,g	13.3 ± 0.5^a^,d^,e^,f^,g*	17.6 ± 0.5^b^,c	17.2 ± 0.7^b^,c	16.4 ± 0.6^b,c*	18.0 ± 0.6^b^,c
Tb.N, #/mm	1.63 ± 0.03^b^,c	1.31 ± 0.02^a^,d^,e^,f^,g*	1.29 ± 0.03^a^,d^,e^,f^,g*	1.66 ± 0.04^b^,c	1.63 ± 0.04^b^,c	1.60 ± 0.04^b^,c	1.68 ± 0.05^b^,c
Tb.Th, mm	0.11 ± 0.00	0.10 ± 0.00	0.10 ± 0.00	0.11 ± 0.00	0.11 ± 0.00	0.10 ± 0.00	0.11 ± 0.00
Tb.Sp, mm	0.46 ± 0.01 ^b^,c	0.55 ± 0.02^a^,d^,e^,f,^,g*	0.55 ± 0.02^a^,d^,e^,f^,g*	0.44 ± 0.02^b^,c	0.47 ± 0.02^b^,c	0.43 ± 0.02 ^b^,c	0.43 ± 0.01 ^b^,c

Values are means ± SE of n = 8–11/group. Letter a–g indicate differences from respectively labeled groups at p < 0.05 or *p < 0.01 (a = vs. SHAM, b = vs. ORX, c = vs. ORX + AN, d = vs. ORX + TE, e = vs. ORX + TE + AN, f = vs. ORX + TREN, g = vs. ORX + TREN + AN). BV/TV = Bone volume fraction, Tb. Th = Trabecular thickness, Tb.N = Trabecular number, Tb.Sp = Trabecular separation.

	SHAM (a)	ORX (b)	ORX+AN (c)	ORX+TE (d)	ORX+TE+AN (e)	ORX+TREN (f)	ORX+TREN+AN (g)
BV/TV, %	17.6 ± 0.6^b^,c	13.3 ± 0.3^a^,d^,e^,f,g	13.3 ± 0.5^a^,d^,e^,f^,g*	17.6 ± 0.5^b^,c	17.2 ± 0.7^b^,c	16.4 ± 0.6^b,c*	18.0 ± 0.6^b^,c
Tb.N, #/mm	1.63 ± 0.03^b^,c	1.31 ± 0.02^a^,d^,e^,f^,g*	1.29 ± 0.03^a^,d^,e^,f^,g*	1.66 ± 0.04^b^,c	1.63 ± 0.04^b^,c	1.60 ± 0.04^b^,c	1.68 ± 0.05^b^,c
Tb.Th, mm	0.11 ± 0.00	0.10 ± 0.00	0.10 ± 0.00	0.11 ± 0.00	0.11 ± 0.00	0.10 ± 0.00	0.11 ± 0.00
Tb.Sp, mm	0.46 ± 0.01 ^b^,c	0.55 ± 0.02^a^,d^,e^,f,^,g*	0.55 ± 0.02^a^,d^,e^,f^,g*	0.44 ± 0.02^b^,c	0.47 ± 0.02^b^,c	0.43 ± 0.02 ^b^,c	0.43 ± 0.01 ^b^,c