Figure EV5. LSD1 and H3K4me2 levels at enhancers shared by low‐ or high‐migrating cells.

• A
  Metagene profiling of LSD1 and H3K4me2 over IgG tags ratio within the 5‐kb window of enhancers shared by low‐migrating Epi‐CTR and ‐HOTΔL cells (red) or by high‐migrating Epi‐HOT and ‐HOTΔP cells (gray). Parallel lines indicate the peak summit in Epi‐CTR, bp stands for base pairs.
• B, C
  Box‐plot of Log₂ LSD1 and H3K4me2 densities at enhancers shared by low‐ (red, N = 775) and high‐migrating cells (gray, N = 53). Central bars represent the median, boxes—lower and upper quartiles and whiskers are set to 1.5*IQR above the third and below the first quartiles. C = CTR, H = HOT, P = HOTΔP, L = HOTΔL. Adj. P‐value was calculated by Bonferroni method, Wilcoxon test and represented only for significant changes observed for LSD1 at enhancers shared by low‐migrating cells.