Table 3.
Glucose homeostasis in the three study groups before and after supplementation with collagen and omega-3 FAs
| Variables |
Control
(n=18) |
Collagen
(n=20) |
Collagen+Omega-3
(n=19) |
P |
|---|---|---|---|---|
| FBG (mg/dl) | ||||
| Baseline | 114.9±27.5 | 108.5±18.9 | 114.7±49.2 | 0.545 a |
| Week-2 | 102.4±17 | 102.2±15.2 | 101.2±19.1 | 0.953 b |
| Week-3 | 102.8±23.8 | 95±13.5 | 93.6±12.2 | 0.227 b |
| Week-2 vs. Baseline | 12.6±35 | 6.6±17.6 | 13.5±46.2 | 0.539 a |
| P (week-2 vs. Baseline)c | 0.091 | 0.991 | 0.768 | |
| Week-3 vs. Baseline | 12.1±34.1 | 13.5±17.4 | 21.1±45.4 | 0.952 a |
| P (week-3 vs. Baseline)c | 0.059 | 0.002 | 0.036 | |
| Insulin (µIU/ml) | ||||
| Baseline | 21.1±26.1 | 17.7±24 | 22.6±18.9 | 0.365 a |
| Week-2 | 18.8±23.4 | 25.4±23.7 | 18.6±17.4 | 0.593 b |
| Week-3 | 22.8±45.6 | 11.3±11.2 | 11.9±13.4 | 0.388 b |
| Week-2 vs. Baseline | 3±34.7 | -7.5±36 | 4±28.4 | 0.178 a |
| P (week-2 vs. Baseline)c | 0.523 | 0.51 | 1 | |
| Week-3 vs. Baseline | -1.1±54.6 | 7.1±24.2 | 10.3±25.8 | 0.283 a |
| P (week-3 vs. Baseline)c | 0.523 | 0.51 | 0.008 | |
| HOMA-IR | ||||
| Baseline | 6.6±8.5 | 5.6±9.9 | 6.4±5.2 | 0.436 a |
| Week-2 | 5.1±7.0 | 6.4±6.2 | 5.1±5.7 | 0.798 b |
| Week-3 | 7.9±20.7 | 2.9±3.1 | 2.8±3.2 | 0.356 b |
| Week-2 vs. Baseline | 1.7±11.4 | -0.7±12.8 | 1.3±8.2 | 0.156 a |
| P (week-2 vs. Baseline)c | 0.381 | 0.51 | 1 | |
| Week-3 vs. Baseline | -1.1±23.1 | 3±10.1 | 3.4±6.6 | 0.292 a |
| P (week-3 vs. Baseline)c | 0.309 | 0.51 | 0.001 |
Values presented as mean ± standard deviation (SD). a: based on kruskal-wallis test; b: based on ANCOVA test adjusted for baseline; c: based on Friedman test. FBG: fasting blood glucose; HOMA-IR: homeostatic model assessment for insulin resistance.