Table 2.

Clinicopathologic and histologic characteristics and the expression of VISTA and PD-L1 by immunohistochemistry in MPM TMA cohort

	Overall n = 319	Epithelioid n = 254	Biphasic n = 41	Sarcomatoid n = 24	p-value*
VISTA raw score, median (range)	50 (0 to 100)	50 (0 to 100)	20 (0 to 95)	0 (0 to 50)	<0.001
PD-L1 raw score, median (range)	0 (0 to 95)	0 (0 to 95)	0 (0 to 95)	20 (0 to 95)	<0.001
Age, median (range)	64 (29 to 85)	63 (29 to 85)	66 (41 to 79)	66 (46 to 78)	0.016
Female, n (%)	82 (25.7)	72 (28.3)	5 (12.2)	5 (20.8)	0.073
Stage, n (%)
1	10	10	0	0	0.023
2	75	67	4	4
3	187	147	27	13
4	47	30	10	7

^*p-values compare rows among the three histology groups

MPM malignant pleural mesothelioma, n number, PD-L1 programmed cell death-ligand 1, TMA tissue microarray, VISTA V-domain Ig suppressor of T-cell activation