TABLE 4.
Multiple Regression Analysis to Determine Most Relevant SARS-CoV-2 Disease Parameters Influence on Peripapillary Vessel Density and Peripapillary Flux Index at 3 Months
| RM1 | RM2 | RM3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| β slope | 95% CI | P | β slope | 95% CI | P | β slope | 95% CI | P | |
| Global VD (%) | −0.306 (Hb) | −0.493 to −0.119 | 0.002 | −0.355 (Hb) | −0.534 to −0.177 | <0.0001 | −1.397 (DM) | −2.176 to −0.618 | 0.001 |
| −0.039 (Age) | −0.065 to −0.012 | 0.004 | −0.323 (Hb) | −0.499 to −0.146 | <0.0001 | ||||
| Global FI (ratio) | 5.485×10−5 (platelets) | −2×10−6 to 1.12×10−4 | 0.060 | −0.001 (Age) | −0.002 to −4.87×10−4 | <0.0001 | −0.025 (DM) | −0.042 to −0.008 | 0.004 |
| −0.011 (AHT) | −0.022 to −0.001 | 0.039 | |||||||
Variables included in regression model 1 (RM1): hemoglobin+ferritin+fibrinogen+APTT+INR+platelets+D-dimer+lymphocytes+disease severity.
Variables included in regression model 2 (RM2): hemoglobin+age+sex.
Variables included in regression model 3 (RM3): hemoglobin+AHT+DM+dyslipidemia.
The variable included in β slope is the resulting variable in the backward steps model.
AHT indicates arterial hypertension; APTT, activated partial thromboplastin time; CI, confidence interval; DM, diabetes mellitus; FI, flux index; Hb, hemoglobin; INR, international normalized ratio; RM, regression model; VD, vessel density.