Table 3.
Type of HY | Onset | Duration | HY degree | Response to glucose | Duration of monitoring | Examples |
---|---|---|---|---|---|---|
Early transitional adaptive | <6–12 h | 12–24h | Mild | Good | 24–48 h | Preterm infants, infant of diabetic mother, intrapartum glucose infusion, hypothermia |
Secondary | 12–24 h | 24–48 h | Mild | Good | 24–48 h | Asphyxia, sepsis, intraventricular bleeding |
Classic transient neonatal | 24–48 h | 48–72 h or more | Moderate to severe. | Requires often higher glucose infusion rate | 48–72 h | Small for gestation |
About 80% are symptomatic | ||||||
Severe recurrent | Variable | >7 d | Severe | Requires higher glucose infusion rates >10–12 | May be days to weeks | Congenital hyperinsulinism, metabolic and endocrine forms |
Modified from Kallem et al. (18).