Figure 1.

Altered taxa abundance of viruses in feces of the three conditional VDR-knockout (VDR^ΔIEC, VDR^ΔPC and VDR^ΔLyz) and control VDR^LoxP mice. (a) Relative viral abundance at the species level (family/f_; s_; the unidentified species were named with super level and other) is shown with the top 10 species, and less abundant species were grouped as “others”. Species were colored using the key as listed on the right side of the figure. Each bar represents an individual mouse. n = 10 each group. VDR^LoxP: 7 females & 3 males; VDR-knockout groups: 5 females & 5 male per group. (b) The virus differential abundance at count per million of the top 10 species in four studied mouse genotypes are illustrated with different colors. Statistical analysis in each group was compared to control VDR^LoxP mice. Mean ± SD, n = 10 per group; ** P-value < 0.01, * P-value < 0.05, Kruskal–Wallis test by ranks