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. 2021 Aug 2;11:686235. doi: 10.3389/fonc.2021.686235

Table 2.

Summary of univariate Kaplan-Meier analysis for PFS for the most significant CT and PET imaging parameters using the median value as the cut-off.

Imaging Median cut-off (direction indicates poor prognosis) Median survival in months (number of patients) Kaplan-Meier p-value Benjamini-Hochberg corrected p-value
Below threshold Above threshold
CT-TA
Kurtosis SSF 6 >0.29 35 (29) 14 (15) 0.049 0.05
PET-TA (no filter)
Entropy >3.79 39 (22) 12 (22) 0.0088 0.01
Skewness <0.95 16 (37) 58 (7) 0.008 0.03
PET conventional analysis
PET 68Ga-DOTATATE-uptake tumor area >52.5 pixels 39 (22) 14 (22) 0.016 0.02
Clinical parameters
Lung metastases >1 35 (29) 14 (15) 0.026 0.04