Table 2.
Summary of univariate Kaplan-Meier analysis for PFS for the most significant CT and PET imaging parameters using the median value as the cut-off.
Imaging | Median cut-off (direction indicates poor prognosis) | Median survival in months (number of patients) | Kaplan-Meier p-value | Benjamini-Hochberg corrected p-value | |
---|---|---|---|---|---|
Below threshold | Above threshold | ||||
CT-TA | |||||
Kurtosis SSF 6 | >0.29 | 35 (29) | 14 (15) | 0.049 | 0.05 |
PET-TA (no filter) | |||||
Entropy | >3.79 | 39 (22) | 12 (22) | 0.0088 | 0.01 |
Skewness | <0.95 | 16 (37) | 58 (7) | 0.008 | 0.03 |
PET conventional analysis | |||||
PET 68Ga-DOTATATE-uptake tumor area | >52.5 pixels | 39 (22) | 14 (22) | 0.016 | 0.02 |
Clinical parameters | |||||
Lung metastases | >1 | 35 (29) | 14 (15) | 0.026 | 0.04 |