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. 2021 Aug 2;11:686235. doi: 10.3389/fonc.2021.686235

Table 3.

Summary of univariate Kaplan-Meier analysis for OS for the most significant CT and PET imaging parameters using the median value as the cut-off.

Imaging Median cut-off (direction indicates poor prognosis) Median survival in months (number of patients) Kaplan-Meier p-value Benjamini-Hochberg corrected p-value
Below threshold Above threshold
CT-TA
Kurtosis SSF 6 >0.29 50 (29) 16 (15) 0.022 0.05
PET-TA (no filter)
Entropy >3.79 53 (22) 22 (22) 0.0058 0.01
Skewness <0.95 28 (37) Not reached (7) 0.034 0.02
PET conventional analysis
PET 68Ga-DOTATATE-uptake tumor area >52.5 pixels Not reached (22) 22 (22) 0.011 0.03
Clinical parameters
Thyroid primary >1 50 (44) 2(5) 0.013 0.04