Table 4.
Blood lipid | Group | Time (week) |
||
---|---|---|---|---|
0w | 6w | 10w | ||
TC | db/m + PBS | 1.61 ± 0.27 | 1.89 ± 0.15 | 1.78 ± 0.16 |
db/db + PBS | 3.45 ± 0.61## | 4.21 ± 0.38## | 3.53 ± 0.16## | |
db/db + KNGT | 3.44 ± 0.43 | 3.15 ± 0.48** | 3.16 ± 0.07* | |
TG | db/m + PBS | 0.87 ± 0.13 | 0.88 ± 0.24 | 1.02 ± 0.02 |
db/db + PBS | 1.62 ± 0.24## | 1.67 ± 0.09## | 1.89 ± 0.07## | |
db/db + KNGT | 1.67 ± 0.16 | 1.40 ± 0.14** | 1.29 ± 0.04** | |
LDL-C | db/m + PBS | 3.11 ± 0.08 | 3.20 ± 0.05 | 3.08 ± 0.02 |
db/db + PBS | 4.43 ± 0.14## | 4.21 ± 0.02## | 4.34 ± 0.08## | |
db/db + KNGT | 4.27 ± 0.10 | 3.57 ± 0.08** | 3.56 ± 0.07** | |
HDL-C | db/m + PBS | 63.02 ± 2.28 | 70.30 ± 2.21 | 72.52 ± 1.37 |
db/db + PBS | 53.97 ± 2.18## | 55.30 ± 0.89## | 56.68 ± 0.69## | |
db/db + KNGT | 55.32 ± 1.99 | 58.28 ± 1.19* | 59.24 ± 0.84* |
Data were analyzed using one-way ANOVA. ##p < 0.01 compared to db/m + PBS mice; *p < 0.05; **p < 0.01 compared to db/db + PBS mice. 0w: n = 6; 6w: n = 6; 10w: n = 3.