Table 8.
Effect of FMT- KNGT on the levels of target bacteria in the faeces of mice by RT-qPCR ( ± s, LogSQ).
| Bacteria | Group | Time (Week) |
||
|---|---|---|---|---|
| 0w | 6w | 10w | ||
| Mucispirillum schaedleri | db/m + PBS | 2.28 ± 0.20 | 2.59 ± 0.22 | 3.01 ± 0.10 |
| db/db + PBS | 3.17 ± 0.48# | 3.60 ± 0.54## | 4.11 ± 0.43## | |
| db/db + KNGT | 2.98 ± 0.33# | 2.88 ± 0.39** | 3.12 ± 0.30** | |
| Clostridium | db/m + PBS | 1.34 ± 0.12 | 1.22 ± 0.11 | 1.16 ± 0.07 |
| db/db + PBS | 1.12 ± 0.08# | 1.02 ± 0.07# | 0.92 ± 0.07# | |
| db/db + KNGT | 1.19 ± 0.14# | 1.43 ± 0.17** | 1.21 ± 0.05** | |
| Sutterella | db/m + PBS | 2.54 ± 0.30 | 2.24 ± 0.22 | 2.02 ± 0.05 |
| db/db + PBS | 2.00 ± 0.25# | 1.64 ± 0.15# | 1.66 ± 0.22# | |
| db/db + KNGT | 2.15 ± 0.31# | 2.05 ± 0.59 | 1.82 ± 0.15 | |
| Bacteroides uniformis | db/m + PBS | 2.27 ± 0.34 | 2.31 ± 0.22 | 1.84 ± 0.09 |
| db/db + PBS | 2.07 ± 0.18 | 2.16 ± 0.14 | 1.65 ± 0.23 | |
| db/db + KNGT | 2.07 ± 0.17 | 2.29 ± 0.17 | 1.79 ± 0.09 | |
| Ruminococcus gnavus | db/m + PBS | 2.83 ± 0.63 | 2.57 ± 0.75 | 2.20 ± 0.61 |
| db/db + PBS | 2.12 ± 0.46# | 1.62 ± 0.28# | 1.23 ± 0.20 | |
| db/db + KNGT | 2.25 ± 0.60 | 2.20 ± 0.61 | 1.72 ± 0.43 | |
| Bacteroides | db/m + PBS | 5.54 ± 0.86 | 5.02 ± 0.23 | 4.47 ± 0.23 |
| db/db + PBS | 4.23 ± 0.31# | 4.68 ± 0.10# | 3.86 ± 0.25 | |
| db/db + KNGT | 4.37 ± 0.36# | 4.78 ± 0.29 | 4.34 ± 0.51 | |
| Faecalibacterium prausnitzii | db/m + PBS | 2.80 ± 0.38 | 2.94 ± 0.36 | 2.91 ± 0.04 |
| db/db + PBS | 2.39 ± 0.51 | 2.19 ± 0.53# | 2.08 ± 0.23# | |
| db/db + KNGT | 2.37 ± 0.43 | 2.50 ± 0.44 | 2.62 ± 0.43 | |
SQ represents the starting template quantity. Data were analyzed using one-way ANOVA. #p < 0.05; ##p < 0.01 compared to db/m + PBS mice; **p < 0.01 compared to db/db + PBS mice. 0w: n = 6, 6w: n = 6, 10w: n = 3.