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. 2021 Aug 2;11:700305. doi: 10.3389/fcimb.2021.700305

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Copyright © 2021 de Barros, Rossoni, Garcia, Kaminski, Loures, Fuchs, Mylonakis and Junqueira

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Macroscopic and histological assessment of candidiasis lesions formed on mice’s dorsum tongue. Mice were treated with PBS (control group), nystatin or CAPE (A–D). Scores and median of macroscopic lesions quantification (A), Yeasts count and hyphae in PAS stained sections (B), and epithelial lesions (C) and inflammatory infiltrate (D) determined in H&E slides (Kruskal-Wallis and Dunn’s posttest; statistically significant differences between groups are represented by different letters).