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. 2021 Aug 2;11:700305. doi: 10.3389/fcimb.2021.700305

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Copyright © 2021 de Barros, Rossoni, Garcia, Kaminski, Loures, Fuchs, Mylonakis and Junqueira

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CAPE increased the expression of antimicrobial peptides genes of G. mellonella at 24h after treatment of CAPE. Relative quantification (log) of galiomicin and gallerimycin for the groups inoculated with PBS (Control), infected with CA70 only (untreated), treated with CAPE, and infected and treated with CAPE [CA70 + CAPE (5 mg/Kg)]. Gene expression was represented as mean and SD. Normalization was done using β-actin gene. Different letters A, B, C and D represent statistically significant differences among the groups. ANOVA and Tukey Tests (p < 0.05).