Table 3.
Case 1 | Case 2 | Case 3 | Case 4 | |
---|---|---|---|---|
CMV | None | None | None | None |
EBV | None | None | None | None |
Infections (other) | C. Difficile | E. Coli UTI and bacteremia | None | None |
Thrombocytopenia | None | Grade 1 | Grade 2 | Grade 2 |
Peripheral neuropathy | None | None | None | None |
Serious bleeding events | None | None | None | None |
Thrombotic event | None | None | None | Device thrombosis* |
CMV, cytomegalovirus tested by PCR; EBV, Epstein-barr virus DNA tested by PCR; UTI, urinary tract infection; thrombocytopenia, CTCAE grading; peripheral neuropathy (self-reported); serious bleeding events (any event requiring transfusion, any overt GI bleeding, any intracranial bleed); thrombotic event, any peripheral or central thrombosis.
the patient developed LVAD thrombosis (HeartMate II) complicated by a stroke and expired.
This occurred 5 months after the last cycle of PI therapy.