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. 2021 Jul 28;14(8):e007433. doi: 10.1161/CIRCHEARTFAILURE.120.007433

Figure 4.

Figure 4.

Positive alcohol by toxicology declined over time (subject to the limitations of the dataset), but all other drugs have increased from 2010 to 2017 (all comparisons over time P<0.0001). The incidence of tetrahydrocannabinol (THC), benzodiazepines, and cocaine has doubled, and amphetamines (combination of all types) have increased >5-fold in the study period while opiate use has nearly tripled.