Table 2.

Relationship Between PD-L1 Gene Amplification and Clinicopathological Features of Lung Squamous Cell Carcinoma

Variable	Total	PD-L1 Amplification				PD-L1 Expression
		No	Yes	χ2	p-value	<1%	1–49%	≥50%	χ2	p-value
Total	164	153	11			86	47	31
Gender
Female	18	15	3	3.495	0.073	6	8	4	3.283	0.194
Male	146	138	8			80	39	27
Age (years)
≤60	87	79	8	6.462	0.176	37	30	20	7.300	0.026
>60	77	74	3			49	17	11
Smoking
Yes	101	94	7	0.728	0.885	60	26	15	5.496	0.064
No	63	59	4			26	21	16
Tumor size
T1	4	4	0	9.847	0.340	1	2	1	20.450	<0.001
T2	75	72	3			28	33	14
T3	85	77	8			57	12	16
Histological grade
1	44	40	4	1.802	0.531	26	10	8	1.347	0.853
2	49	45	4			24	15	10
3	71	68	3			36	22	13
Stage
I	39	39	0	52.897	<0.001	27	9	3	15.391	0.017
II	84	81	3			45	23	16
III	37	32	5			13	12	12
IV	4	1	3			1	3	0
Lymph node metastasis
Yes	71	61	10	49.639	0.001	14	34	23	53.774	<0.001
No	93	92	1			72	13	8
Metastasis
Yes	4	1	3	30.973	<0.001	1	3	0	4.436	0.109
No	160	152	8			85	44	31
Relapse
Yes	7	7	0	1.501	0.468	3	3	1	0.725	0.696
No	157	146	11			83	44	30