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[Preprint]. 2021 Aug 9:2021.08.05.21261643. [Version 1] doi: 10.1101/2021.08.05.21261643

Table 5.

Risk of death following COVID-19 in patients treated with CD20 inhibitors for neurologic disease indications versus comparators.

CD20 Inhibitor-Treated Neurologic Disease Cases (n=43) Matched Comparators (n=211)
Deaths, n (%) 2 (5) 4 (2)
Total follow-up time (person-days) 6551 34051
Incidence rate/1000 days (95% CI) 0.3 (0.0 to 0.7) 0.1 (0.0 to 0.2)
Unadjusted HR (95% CI) 2.41 (0.66 to 8.77) Ref
Adjusted model 1 HR (95% CI)* NR Ref
Adjusted model 2 HR (95% CI) NR Ref
Adjusted model 3 HR (95% CI) NR Ref

HR, hazard ratio; CI, confidence interval; BMI, body mass index; CCI, Charlson comorbidity index; Ref, reference; NR, not reported

*

Model 1 adjusted for age. Model 2 adjusted for age and race. Model 3 adjusted for age, race, BMI, and CCI (dichotomized as <2 or ≥2). Adjusted models not reported due to insufficient number of outcomes (<7 outcomes per adjusted covariate).