Table 5.
Risk of death following COVID-19 in patients treated with CD20 inhibitors for neurologic disease indications versus comparators.
| CD20 Inhibitor-Treated Neurologic Disease Cases (n=43) | Matched Comparators (n=211) | |
|---|---|---|
| Deaths, n (%) | 2 (5) | 4 (2) | 
| Total follow-up time (person-days) | 6551 | 34051 | 
| Incidence rate/1000 days (95% CI) | 0.3 (0.0 to 0.7) | 0.1 (0.0 to 0.2) | 
| Unadjusted HR (95% CI) | 2.41 (0.66 to 8.77) | Ref | 
| Adjusted model 1 HR (95% CI)* | NR | Ref | 
| Adjusted model 2 HR (95% CI) | NR | Ref | 
| Adjusted model 3 HR (95% CI) | NR | Ref | 
HR, hazard ratio; CI, confidence interval; BMI, body mass index; CCI, Charlson comorbidity index; Ref, reference; NR, not reported
Model 1 adjusted for age. Model 2 adjusted for age and race. Model 3 adjusted for age, race, BMI, and CCI (dichotomized as <2 or ≥2). Adjusted models not reported due to insufficient number of outcomes (<7 outcomes per adjusted covariate).