Table 3.

Longitudinal analysis of vaccine effectiveness against breakthrough infections in Minnesota, split by month.

Month	mRNA-1273 Incidence Rate Events/Person-Days [Per 1000 Person-Days] (# Individuals Contributing)	BNT162b2 Incidence Rate Events/Person-Days [Per 1000 Person-Days] (# Individuals Contributing)	Unvaccinated Incidence Rate Events/Person- Days [Per1000 Person-Days] (# Individuals Contributing)	IRR mRNA-1273 / Unvax	IRR BNT162b2 / Unvax	IRR mRNA-1273 / BNT162b2
February	0/14106.0 [0] (n = 1574)	0/15953.0 [0] (n = 1552)	1/15813.0 [0.063] (n = 1595)	0 (0, 44)	0 (0, 39)	N/A
March	3/123184.0 [0.024] (n = 6956)	4/135794.0 [0.029] (n = 6590)	37/137738.0 [0.27] (n = 7411)	0.091 (0.018, 0.29)	0.11 (0.028, 0.31)	0.83 (0.12, 4.9)
April	7/302898.0 [0.023] (n = 14463)	11/330239.0 [0.033] (n = 15129)	93/343015.0 [0.27] (n = 16321)	0.085 (0.033, 0.18)	0.12 (0.059, 0.23)	0.69 (0.23, 2)
May	5/508598.0 [0.0098] (n = 18449)	13/533743.0 [0.024] (n = 19503)	82/575635.0 [0.14] (n = 21212)	0.069 (0.022, 0.17)	0.17 (0.087, 0.31)	0.4 (0.11, 1.2)
June	8/575955.0 [0.014] (n = 20583)	4/598933.0 [0.0067] (n = 21411)	24/659357.0 [0.036] (n = 23780)	0.38 (0.15, 0.88)	0.18 (0.046, 0.53)	2.1 (0.56, 9.4)
July	15/627756.0 [0.024] (n = 21079)	38/652459.0 [0.058] (n = 21946)	73/724645.0 [0.1] (n = 24444)	0.24 (0.13, 0.42)	0.58 (0.38, 0.87)	0.41 (0.21, 0.76)