Table 4.

Longitudinal analysis of vaccine effectiveness against hospitalizations associated with breakthrough infections in Minnesota, split by month.

Month	mRNA-1273 Incidence Rate Events/Person-Days [Per 1000 Person-Days] (# Individuals Contributing)	BNT162b2 Incidence Rate Events/Person-Days [Per 1000 Person-Days] (# Individuals Contributing)	Unvaccinated Incidence Rate Events/Person-Days [Per 1000 Person-Days] (# Individuals Contributing)	IRR mRNA-1273 / Unvax	IRR BNT162b2 / Unvax	IRR mRNA-1273 / BNT162b2
February	0/14117.0 [0] (n = 1575)	0/15974.0 [0] (n = 1554)	0/15848.0 [0] (n = 1601)	N/A	N/A	N/A
March	1/123233.0 [0.0081] (n = 6958)	1/135930.0 [0.0074] (n = 6594)	9/138478.0 [0.065] (n = 7435)	0.12 (0.0028, 0.9)	0.11 (0.0026, 0.82)	1.1 (0.014, 87)
April	1/303102.0 [0.0033] (n = 14469)	2/330648.0 [0.006] (n = 15144)	20/346174.0 [0.058] (n = 16422)	0.057 (0.0014, 0.36)	0.1 (0.012, 0.43)	0.55 (0.0092, 10)
May	1/509149.0 [0.002] (n = 18465)	3/534837.0 [0.0056] (n = 19536)	25/582284.0 [0.043] (n = 21411)	0.046 (0.0011, 0.28)	0.13 (0.025, 0.43)	0.35 (0.0067, 4.4)
June	0/576677.0 [0] (n = 20603)	1/600226.0 [0.0017] (n = 21455)	7/667073.0 [0.01] (n = 24039)	0 (0, 0.8)	0.16 (0.0035, 12)	0 (0, 41)
July	3/628674.0 [0.0048] (n = 21107)	4/654236.0 [0.0061] (n = 21994)	18/733732.0 [0.025] (n = 24721)	0.19 (0.037, 0.67)	0.25 (0.061, 0.76)	0.78 (0.11, 4.6)