Table 5.
Comparison of incidence rates of positive SARS-CoV-2 testing between mRNA-1273 cohort versus BNT162b2 cohort within each individual state and across all states.
| Time Period | State | mRNA-12732 Incidence Rate Events/Person-Days [Per 1000 Person-Days] (# Individuals Contributing) |
BNT162b2 Incidence Rate Events/Person-Days [Per 1000 Person-Days] (# Individuals Contributing) |
IRR mRNA-1273 / BNT162b2 (95% CI) |
|---|---|---|---|---|
| Days 1–7 following first dose (across entire study period) | Minnesota | 74/180810 [0.41] (n = 25869) | 58/180675 [0.32] (n = 25869) | 1.3 (0.89, 1.8) |
| Florida | 10/30815 [0.32] (n = 4412) | 4/30754 [0.13] (n = 4412) | 2.5 (0.72, 11) | |
| Wisconsin | 10/52771 [0.19] (n = 7544) | 13/52761 [0.25] (n = 7544) | 0.77 (0.3, 1.9) | |
| Arizona | 5/26710 [0.19] (n = 3817) | 8/26673 [0.3] (n = 3817) | 0.62 (0.16, 2.2) | |
| Iowa | 0/6706 [0] (n = 958) | 3/6694 [0.45] (n = 958) | 0 (0, 2.4) | |
| All states | 99/306873 [0.32] (n = 43895) | 87/306621 [0.28] (n = 43895) | 1.1 (0.84, 1.5) | |
| On or after 14 days following the second dose (across entire study period) | Minnesota | 38/2214873.0 [0.017] (n = 21179) | 72/2332005.0 [0.031] (n = 22064) | 0.56 (0.36, 0.83) |
| Florida | 37/434006.0 [0.085] (n = 3405) | 90/441216.0 [0.2] (n = 3617) | 0.42 (0.28, 0.62) | |
| Wisconsin | 15/736959.0 [0.02] (n = 6327) | 30/770231.0 [0.039] (n = 6692) | 0.52 (0.26, 1) | |
| Arizona | 8/398701.0 [0.02] (n = 3198) | 21/407607.0 [0.052] (n = 3251) | 0.39 (0.15, 0.92) | |
| Iowa | 0/90155.0 [0] (n = 754) | 4/97760.0 [0.041] (n = 818) | 0 (0, 1.6) | |
| All states | 105/4010220.0 [0.026] (n = 35902) | 219/4195555.0 [0.052] (n = 37573) | 0.5 (0.39, 0.64) | |
| On or after the 14 days following the second dose (in July only) | Minnesota | 15/627756.0 [0.024] (n = 21079) | 38/652459.0 [0.058] (n = 21946) | 0.41 (0.21, 0.76) |
| Florida | 26/100940.0 [0.26] (n = 3379) | 70/106535.0 [0.66] (n = 3583) | 0.39 (0.24, 0.62) | |
| Wisconsin | 9/187855.0 [0.048] (n = 6284) | 18/198532.0 [0.091] (n = 6644) | 0.53 (0.21, 1.2) | |
| Arizona | 5/95238.0 [0.053] (n = 3182) | 10/96602.0 [0.1] (n = 3228) | 0.51 (0.14, 1.6) | |
| Iowa | 0/22590.0 [0] (n = 753) | 1/24368.0 [0.041] (n = 813) | 0 (0, 42) | |
| All states | 58/1065321.0 [0.054] (n = 35710) | 138/1112136.0 [0.12] (n = 37337) | 0.44 (0.32, 0.6) |