Table 1.
Average data for weight, age resting membrane potential (RMP), holding current (IHold), and input resistance (RIN) in control and eDNE groups in each of the two age groups
| Control | eDNE | n (control:eDNE) | p value | |
|---|---|---|---|---|
| Weight (g) | ||||
| P1–P5 | 9.01 ± 0.6 | 8.6 ± 0.6 | 8:8 pups | <0.0001 |
| P10–P12 | 26.59 ± 3.3 | 31.0 ± 1.9 | 9:8 pups | |
| Age (d) | ||||
| P1–P5 | 3.25 ± 0.5 | 2.88 ± 0.5 | 8:8 pups | <0.0001 |
| P10–P12 | 11.11 ± 0.3 | 11.00 ± 0.3 | 9:8 pups | |
| RMP (mV) | ||||
| P1–P5 | –60.75 ± 1.5 | –57.88 ± 1.6 | 16:16 cells | 0.6435 |
| P10–P12 | –60.44 ± 1.8 | –59.00 ± 2.1 | 16:16 cells | |
| RIN (MW) | ||||
| P1–P5 | 109.2 ± 12.1 | 128.4 ± 10.5* | 16:16 cells | 0.0408 |
| P10–P12 | 87.1 ± 10.3 | 92.25 ± 11.5 | 16:16 cells | |
| IHold (pA) | ||||
| P1–P5 | –152.5 ± 25.2 | −165.6 ± 21.6 | 16:16 cells | 0.7411 |
| P10–P12 | −167.8 ± 30.8 | −129.1 ± 31.3 | 16:16 cells |
All values are mean ± SD. Bold numbers indicate difference between P1–P2 and P10–P12 age groups; * indicates significant difference between eDNE at P1–P5 and control at P10–P12.