Table 1.

Treatment outcomes of amantadine in children and adolescents, overall and by diagnosis

Diagnosis	Total	Success	Minimal	Failure	SE D/C
Full study group	297	185 (62.3%)	61 (20.5%)	34 (11.4%)	17 (5.7%)
ADHD	251	162 (64.5%)	52 (20.7%)	27 (10.8%)	10 (4.0%)
ODD/CD	190	114 (60%)	43 (22.6%)	19 (10%)	14 (7.4%)
Depressive disorder	36	24 (66.7%)	10 (27.8%)	2 (5.6%)	0
Anxiety disorder/OCD	92	62 (67.4%)	17 (18.5%)	9 (9.8%)	4 (4.4%)
Autistic spectrum disorder	59	40 (67.8%)	12 (20.3%)	2 (3.4%)	5 (8.5%)
PTSD	18	10 (55.6%)	2 (11.1%)	6 (33.3%)	0
Intellectual disability	43	28 (65.1%)	10 (23.3%)	4 (9.3%)	1 (2.3%)

ADHD indicates attention deficit/hyperactivity disorder (combined and inattentive); OCD, obsessive-compulsive disorder; ODD/CD, oppositional defiant disorder/conduct disorder; PTSD, posttraumatic stress disorder; SE D/C, side effect discontinuation.