Table 3.
Reported symptom improvement by psychiatric diagnosis after amantadine
| Diagnosis | Impulsivity | Irritability/anger | Focus/concentration | Aggression/outbursts | Thought processing |
|---|---|---|---|---|---|
| ADHD (n = 214) | 176 (82%) | 112 (52%) | 109 (51%) | 63 (29%) | 44 (21%) |
| ODD/CD (n = 157) | 130 (83%) | 85 (54%) | 69 (44%) | 47 (30%) | 31 (20%) |
| Depressive disorder (n = 34) | 25 (74%) | 18 (53%) | 12 (35%) | 17 (50%) | 4 (12%) |
| Anxiety disorder/OCD (n = 79) | 65 (82%) | 44 (56%) | 29 (37%) | 13 (16%) | 24 (30%) |
| ASD (n = 52) | 41 (79%) | 29 (56%) | 28 (54%) | 7 (13%) | 10 (19%) |
| PTSD (n = 12) | 10 (83%) | 6 (50%) | 7 (58%) | 1 (8%) | 4 (33%) |
| Intellectual disability (n = 38) | 32 (84%) | 20 (53%) | 10 (26%) | 10 (26%) | 10 (26%) |
ADHD indicates attention deficit/hyperactivity disorder; ASD, autism spectrum disorder; OCD, obsessive-compulsive disorder; ODD/CD, oppositional defiant disorder/conduct disorder; PTSD, posttraumatic stress disorder.