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. 2021 Aug 2;18(8):e1003708. doi: 10.1371/journal.pmed.1003708

Table 1. Characteristics of patients per studied symptom cohort at time of index consultation, n (%).

Demographic and clinical variables Abdominal bloating/distension n/(%) Abdominal pain n/(%) Change in bowel habit n/(%) Dyspepsia n/(%) Dysphagia n/(%) Rectal bleeding n/(%)
Total 100,856 (100.0) 890,490 (100.0) 106,715 (100.0) 517,326 (100.0) 86,193 (100.0) 235,094 (100.0)
Sex
    Female 73,583 (73.0) 561,373 (63.0) 61,476 (57.6) 300,053 (58.0) 48,759 (56.6) 118,371 (50.4)
Age (years)
    Median (IQR) 53 (43–66) 52 (41–66) 63 (52–73) 56 (44–68) 63 (51–75) 56 (46–69)
Age group (years)
    30–39 17,709 (17.6) 198,916 (22.3) 6,666 (6.2) 79,425 (15.4) 6,988 (8.1) 39,042 (16.6)
    40–49 23,915 (23.7) 198,502 (22.3) 14,596 (13.7) 105,389 (20.4) 12,705 (14.7) 47,676 (20.3)
    50–59 21,124 (20.9) 173,876 (19.5) 23,103 (21.6) 108,031 (20.9) 16,496 (19.1) 48,879 (20.8)
    60–69 18,029 (17.9) 152,039 (17.1) 26,165 (24.5) 108,086 (20.9) 18,372 (21.3) 44,231 (18.8)
    70–79 13,354 (13.2) 109,848 (12.3) 23,489 (22.0) 78,729 (15.2) 17,566 (20.4) 34,472 (14.7)
    80+ 6,725 (6.7) 57,309 (6.4) 12,696 (11.9) 37,666 (7.3) 14,066 (16.3) 20,794 (8.8)
Number of abdominal symptoms at index *
    1 31,948 (31.7) 881,099 (98.9) 102,613 (96.2) 452,348 (87.4) 84,259 (97.8) 229,746 (97.7)
    2 66,154 (65.6) 8,156 (0.9) 3,552 (3.3) 62,917 (12.2) 1,812 (2.1) 4,942 (2.1)
    3+ 2,754 (2.7) 1,235 (0.1) 550 (0.5) 2,061 (0.4) 122 (0.1) 406 (0.2)
Other abdominal symptoms **
None 24,899 (24.7) 819,828 (92.1) 86,118 (80.7) 389,398 (75.3) 71,515 (83.0) 202,794 (86.3)
Any 75,957 (75.3) 70,662 (7.9) 20,597 (19.3) 127,928 (24.7) 14,678 (17.0) 32,300 (13.7)
    Abdominal bloating/distension 10,572 (1.2) 1,715 (1.6) 60,690 (11.7) 852 (1.0) 2,029 (0.9)
    Abdominal pain 16,650 (16.5) 12,701 (11.9) 59,594 (11.5) 7,463 (8.7) 20,537 (8.7)
    Change in bowel habit 1,418 (1.4) 7,399 (0.8) 4,163 (0.8) 714 (0.8) 3,056 (1.3)
    Dyspepsia 70,679 (70.1) 44,309 (5.0) 6,068 (5.7) 6,753 (7.8) 10,286 (4.4)
    Dysphagia 759 (0.8) 4,552 (0.5) 793 (0.7) 9,356 (1.8) 1,361 (0.6)
    Rectal bleeding 1,941 (1.9) 13,565 (1.5) 3,307 (3.1) 8,022 (1.6) 1,336 (1.6)

* Number of symptoms recorded simultaneously on index consultation date.

** Symptoms recorded in the same consultations or up to a year prior. Note that patients can have multiple abdominal symptoms in the previous year, and, therefore, %s may not add to 100.