Therapeutic schedule	Level of evidence	Strength of recommendation
2.1	Granulomatous lobular mastitis
2.1.1	Corticosteroids[7],∗	III	B
2.2	Periductal mastitis
2.2.1	Anti-infective treatment during acute inflammation[3],†	II	A
2.2.2	Anti-mycobacterial drugs for periductal mastitis with fistula formation or ulceration[8,9],‡	III	B

^∗Prednisone or methylprednisolone can be used. The usual dosage is prednisone 0.75 mg·kg⁻¹·day⁻¹, a 2-week course being recommended. The dose should be reduced gradually once the symptoms have resolved. The time to complete resolution is highly variable (1.5–20 months). ^†Broad-spectrum antibiotics are used to control the inflammatory response in the acute phase; however, antibiotic treatment alone cannot cure this condition. ^‡Isoniazid (300 mg/day), rifampicin (450 mg/day) combined with ethambutol (750 mg/day) or pyrazinamide (750 mg/day). Published reports recommend treatment for 9 to 12 months.