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. 2021 Aug 12;12(8):e00386. doi: 10.14309/ctg.0000000000000386

Table 3.

Associations between the biomarkers and clinicopathological parameters in the colorectal polyps' group

Colorectal polyps CEA CA19-9 FIT Septin9 SDC2 BCAT1 Composite score (P)
Number
 Single (N = 45)
  Mean ± SD 2.6 ± 2.0 13.3 ± 10.4 1.1 ± 0.3 44.3 ± 1.5 44.8 ± 1.1 44.9 ± 0.8 0.3 ± 0.7
  Positive (%) 5 (11.1) 3 (6.7) 3 (6.7) 1 (2.2) 2 (4.4) 1 (2.2) 1 (2.2)
 Multiple (N = 85)
  Mean ± SD 5.7 ± 22.7 10.5 ± 8.0 1.2 ± 0.4* 44.0 ± 2.1 44.6 ± 1.5 44.7 ± 1.1 0.4 ± 0.9
  Positive (%) 17 (20) 4 (4.7) 17 (20) 6 (7.1) 10 (11.8) 7 (8.2) 3 (3.5)
Size
 ≤1 cm (N = 93)
  Mean ± SD 5.4 ± 21.7 11.3 ± 9.1 1.1 ± 0.3 44.1 ± 2.0 44.7 ± 1.4 44.8 ± 0.8 0.4 ± 0.9
  Positive (%) 18 (19.4) 6 (6.5) 10 (10.8) 4 (4.3) 7 (7.5) 5 (5.4) 3 (3.2)
 >1 cm (N = 37)
  Mean ± SD 2.8 ± 1.7 11.9 ± 8.7 1.3 ± 0.5* 44.3 ± 1.7 44.6 ± 1.2 44.7 ± 1.32 0.3 ± 0.8
  Positive (%) 4 (10.8) 1 (2.7) 10 (27)* 3 (8.1) 5 (13.5) 3 (8.1) 1 (2.7)
Advanced adenoma
 No (N = 83)
  Mean ± SD 3.0 ± 2.5 11.8 ± 10.0 1.1 ± 0.5 44.1 ± 2.1 44.6 ± 1.5 44.8 ± 0.9 0.36 ± 0.9
  Positive (%) 13 (15.7) 6 (7.2) 7 (8.4) 4 (4.8) 7 (8.4) 5 (6.0) 3 (3.6)
 Yes (N = 47)
  Mean ± SD 7.6 ± 30.4 10.9 ± 7.0 1.3 ± 0.3* 44.3 ± 1.6 44.7 ± 1.0 44.7 ± 1.2 0.3 ± 0.7
  Positive (%) 9 (19.1) 1 (2.1) 13 (27.7)* 3 (6.4) 5 (10.6) 3 (6.4) 1 (2.1)

CA19-9, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen; FIT, fecal immunochemical test for hemoglobin.

*P < 0.05.