Table 3.
Associations between the biomarkers and clinicopathological parameters in the colorectal polyps' group
Colorectal polyps | CEA | CA19-9 | FIT | Septin9 | SDC2 | BCAT1 | Composite score (P) |
Number | |||||||
Single (N = 45) | |||||||
Mean ± SD | 2.6 ± 2.0 | 13.3 ± 10.4 | 1.1 ± 0.3 | 44.3 ± 1.5 | 44.8 ± 1.1 | 44.9 ± 0.8 | 0.3 ± 0.7 |
Positive (%) | 5 (11.1) | 3 (6.7) | 3 (6.7) | 1 (2.2) | 2 (4.4) | 1 (2.2) | 1 (2.2) |
Multiple (N = 85) | |||||||
Mean ± SD | 5.7 ± 22.7 | 10.5 ± 8.0 | 1.2 ± 0.4* | 44.0 ± 2.1 | 44.6 ± 1.5 | 44.7 ± 1.1 | 0.4 ± 0.9 |
Positive (%) | 17 (20) | 4 (4.7) | 17 (20) | 6 (7.1) | 10 (11.8) | 7 (8.2) | 3 (3.5) |
Size | |||||||
≤1 cm (N = 93) | |||||||
Mean ± SD | 5.4 ± 21.7 | 11.3 ± 9.1 | 1.1 ± 0.3 | 44.1 ± 2.0 | 44.7 ± 1.4 | 44.8 ± 0.8 | 0.4 ± 0.9 |
Positive (%) | 18 (19.4) | 6 (6.5) | 10 (10.8) | 4 (4.3) | 7 (7.5) | 5 (5.4) | 3 (3.2) |
>1 cm (N = 37) | |||||||
Mean ± SD | 2.8 ± 1.7 | 11.9 ± 8.7 | 1.3 ± 0.5* | 44.3 ± 1.7 | 44.6 ± 1.2 | 44.7 ± 1.32 | 0.3 ± 0.8 |
Positive (%) | 4 (10.8) | 1 (2.7) | 10 (27)* | 3 (8.1) | 5 (13.5) | 3 (8.1) | 1 (2.7) |
Advanced adenoma | |||||||
No (N = 83) | |||||||
Mean ± SD | 3.0 ± 2.5 | 11.8 ± 10.0 | 1.1 ± 0.5 | 44.1 ± 2.1 | 44.6 ± 1.5 | 44.8 ± 0.9 | 0.36 ± 0.9 |
Positive (%) | 13 (15.7) | 6 (7.2) | 7 (8.4) | 4 (4.8) | 7 (8.4) | 5 (6.0) | 3 (3.6) |
Yes (N = 47) | |||||||
Mean ± SD | 7.6 ± 30.4 | 10.9 ± 7.0 | 1.3 ± 0.3* | 44.3 ± 1.6 | 44.7 ± 1.0 | 44.7 ± 1.2 | 0.3 ± 0.7 |
Positive (%) | 9 (19.1) | 1 (2.1) | 13 (27.7)* | 3 (6.4) | 5 (10.6) | 3 (6.4) | 1 (2.1) |
CA19-9, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen; FIT, fecal immunochemical test for hemoglobin.
*P < 0.05.