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. 2021 Jul 1;5(4):e161. doi: 10.1097/EE9.0000000000000161

Table 4.

Phthalate metabolite concentration and odds of preschool ADHD by child sex, using augmented product term models, with sex-interaction products for phthalate and for maternal education.

Adjusted for covariatesa Adjusted for covariates and correlated phthalatesb
Casesc Boys Girls Boys Girls
Phthalate Boys Girls OR (95% CI)d OR (95% CI)d P e OR (95% CI)d OR (95% CI)d P e
MEP 142 111 1.03 (0.89 to 1.19) 1.03 (0.88 to 1.21) 0.97
MiBP 142 111 1.17 (0.92 to 1.50) 0.97 (0.73 to 1.29) 0.33 0.98 (0.71 to 1.35) 1.00 (0.71 to 1.41) 0.93
MnBP 142 111 1.42 (1.07 to 1.88) 0.93 (0.68 to 1.28) 0.05 1.43 (0.97 to 2.10) 0.82 (0.51 to 1.31) 0.07
MBzP 142 111 1.20 (0.95 to 1.53) 1.06 (0.82 to 1.37) 0.47 1.01 (0.74 to 1.39) 1.17 (0.84 to 1.65) 0.53
∑DEHP 142 111 1.32 (1.00 to 1.74) 1.10 (0.78 to 1.55) 0.42 1.28 (0.95 to 1.73) 1.03 (0.70 to 1.51) 0.37
∑DiNP 142 111 1.22 (0.88 to 1.68) 1.17 (0.83 to 1.64) 0.86 1.10 (0.78 to 1.55) 1.15 (0.79 to 1.69) 0.85

aAdjusted for specific gravity, analytic batch, child sex and maternal age, education, parity, depression during pregnancy, and maternal ADHD-like symptoms.

bAdjusted for specific gravity, analytic batch, child sex and maternal age, education, parity, depression during pregnancy, maternal ADHD-like symptoms, and additionally adjusted for correlated metabolites (a) MiBP, MnBP, and MBzP coadjusted for one another; (b) ∑DEHP and ∑DiNP coadjusted for each other.

cNumber with no missing exposure or covariates.

dPer 1 natural log-unit increase in biomarker.

eP for sex*phthalate interaction in linear regression models.